ResultsĪllelic variations of both rs5522 and rs5569 were significant when compared to PPI-SF total score and the fearless dominance component of the PPI-SF. Participants then completed the Psychopathic Personality Inventory–Short Form (PPI-SF) and the Tower of Hanoi. Methodsįifty-seven healthy participants from the community provided a saliva sample for SNP sampling of rs5522 and rs5569. The purpose is to examine if allelic variations in single nucleotide polymorphisms related to norepinephrine and mineralocorticoid receptors play a role in the display of psychopathic traits and executive functions. Among other genes and biomarkers relevant to the amygdala, norepinephrine and mineralocorticoid receptors might both play a role in psychopathy due to their association with traits peripheral to psychopathy. Past findings support a relationship between abnormalities in the amygdala and the presence of psychopathic traits. Influence of allelic variations in relation to norepinephrine and mineralocorticoid receptors on psychopathic traits: a pilot study. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

Department of Psychiatry & Neuropsychology, University of Maastricht, Netherlands DOI 10.7717/peerj.4528 Published Accepted Received Academic Editor Jafri Abdullah Subject Areas Genetics, Neuroscience, Psychiatry and Psychology Keywords Psychopathic traits, Executive functions, Mineralocorticoid receptor, Single nucleotide polymorphism, Norepinephrine Copyright © 2018 Durand Licence This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed.

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